Diagnostic markers for platelet function and methods of use

US11008619B2 · kind B2 · utility

Assignee

• Duke University · US

Inventors

• Geoffrey S. Ginsburg · Durham, US
• Joseph E. Lucas · Chapel Hill, US
• Thomas L. Ortel · Mebane, US
• Richard Becker · Burghausen, DE
• Deepak Voora · Chapel Hill, US
• Jen-Tsan Chi · Chapel Hill, US

Key dates

• Filing date: May 16, 2019
• Grant date: May 18, 2021
• Expiry date: Jun 4, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to antiplatelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.