Methods of detecting, diagnosing, and treating carotid plaque vulnerability

US11009514B2 · kind B2 · utility

Assignees

• OCHSNER HEALTH SYSTEM · US
• BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE · US
• The Administrators of the Tulane Educational Fund · US

Inventors

• Hernan Bazan · New Orleans, US
• Yan Lu · Mountain View, US
• Song Hong · New Orleans, US
• Zhide Fang · New Orleans, US
• Bokkyoo Jun · New Orleans, US
• Thomas Cooper Woods · New Orleans, US

Key dates

• Filing date: Jun 22, 2018
• Grant date: May 18, 2021
• Expiry date: Feb 27, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed are methods of, and assay and kits for, detecting and diagnosing methods of detecting, diagnosing, vulnerable carotid artery disease capable of becoming acutely symptomatic using the levels of Resolvin D1 (RvD1), docosahexaenoic acid (DHA), and arachidonic acid (AA). Also disclosed are methods of treating carotid artery disease and methods of identifying agents for use in the treatment of carotid artery disease.