Compounds supports hematopoietic stem cells and red blood cells

US11013704B2 · kind B2 · utility

Assignee

• The Board of Regents of the University of Texas System · US

Inventors

• Chengcheng Zhang · Dallas, US
• Yi Liu · Hsinchu, TW
• Junke Zheng · Shanghai, CN
• Mi Deng · Plano, US
• Chuo Chen · Dallas, US
• Jiawei Liu · Shanghai, CN

Key dates

• Filing date: May 12, 2015
• Grant date: May 25, 2021
• Expiry date: Dec 28, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C279/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to methods of using a compound to induce regeneration of hematopoietic stem cells or increase the recovery of red blood cells. In some aspects, the present methods can be used to with or in place of erythropoietin in patients to mitigate the side effects of erythropoietin.