Compositions and methods of enhancing immunogenicity of polysaccharide protein conjugates
US11013799B2 · kind B2 · utility
2Cited by
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19Claims
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Key dates
| Filing date | May 8, 2015 |
| Grant date | May 25, 2021 |
| Priority date | — |
| Expiry date | Jan 8, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2720/12333
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for enhancing immunogenicity of polysaccharide antigens. Immunogenic compositions and vaccines comprising polysaccharide-protein conjugates comprising a chimeric carrier protein having a universal epitope are provided. Methods of preparing the compositions, and methods for treating or preventing bacterial infections are further provided. The compositions and methods are useful for enhancing immune response in young children, elderly and immunocompromised individuals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.