TRPA1 and TRPV4 inhibitors and methods of using the same for organ-specific inflammation and itch
US11014896B2 · kind B2 · utility
0Cited by
7References
16Claims
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Key dates
| Filing date | Apr 22, 2019 |
| Grant date | May 25, 2021 |
| Priority date | — |
| Expiry date | Apr 22, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods of treating and/or preventing dermatological disorders. Provided are methods of reducing skin inflammation, reducing pain, and/or reducing itch in a subject in need thereof. The methods may include administering to the subject an effective amount of a TRPA1 and/or TRPV4 inhibitor. Further provided are compositions including a TRPA1 and/or TRPV4 inhibitor compound in combination with a carrier, vehicle, or diluent that is suitable for topical application.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.