Method, compositions and device for nano-enhanced opto-chemical trans-differentiation of cells and tissues
US11020359B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 10, 2018 |
| Grant date | Jun 1, 2021 |
| Priority date | — |
| Expiry date | Dec 10, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02F1/365
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel nanomaterial-molecular compositions, methods and devices thereof for efficient and targeted trans-differentiation of cells including fibroblasts and glia into neurons, both in vitro as well as in situ and in-vivo, which is of great importance for cell replacement therapies. Specifically, the invention provides a nanomaterial-molecular composition, device and method for targeted nano-enhanced opto-chemical trans-differentiation of fibroblasts/glia to neurons in the central and peripheral nervous system for restoration of neural functions in patients by delivery of nanomaterial-molecular composition, followed by optical illumination.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.