Preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles

US11021452B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Christopher Koradin · Ludwigshafen, DE
• Wassilios Grammenos · Ludwigshafen, DE
• Michael Rack · Eppelheim, DE
• Kailaskumar Borate · Navi Mumbai, IN
• Roland Goetz · Ludwigshafen, DE

Key dates

• Filing date: Jul 21, 2018
• Grant date: Jun 1, 2021
• Expiry date: Jul 21, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D271/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles (compounds I), which can be obtained through reaction of hydroxyamidine compounds of formula II with trifluoroacetyl halides IIa.