Patent · US Active

Crystalline forms of 4-(tert-butoxyamino)-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine methanesulfonic acid salt

US11021464B2 · kind B2 · utility

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20Claims

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Assignees

Inventors

Ticong Huang · 安丰镇, CN
Huifeng Xiao · Lianyungang, CN
Rui Zhao · Beijing, CN
Fei Liu · Nanjing, CN
Wei Wei · Lo Wu, CN
Hongjiang Xu · Lianyungang, CN
Xiaojin Wang · Lianyungang, CN
Jingli Wu · Lianyungang, CN

Key dates

Filing date	Jan 22, 2018
Grant date	Jun 1, 2021
Priority date	—
Expiry date	Jan 22, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention discloses a crystal of 4-(tert-butoxyamino)-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine compound, a mesylate salt and crystal thereof, a preparation method thereof, a composition containing thereof, and a use thereof for inhibiting activity of mutant IDH2 and treating cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.