Patent · US Active

IRE1 small molecule inhibitors

US11021466B2 · kind B2 · utility

1Cited by

8References

18Claims

0Family size

Assignee

Cornell University · IT

Inventors

Joseph P. Vacca · Telford, US
Dansu Li · New York, US
Sarah Elizabeth Bettigole · New York, US

Key dates

Filing date	Aug 16, 2019
Grant date	Jun 1, 2021
Priority date	—
Expiry date	Aug 16, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are small molecule inhibitors for the targeting or IRE1 protein family members. Binding may be direct or indirect. Further provided herein are methods of using IRE1 small molecule inhibitors for use in treating or ameliorating cancer in a subject. Moreover, IRE1 small molecule inhibitors described herein are for the treatment of cancer, where the cancer is a solid or hematologic cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.