Patent · US Active

Anti-TIGIT antibodies and methods of use thereof

US11021537B2 · kind B2 · utility

1Cited by
13References
70Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 1, 2018
Grant dateJun 1, 2021
Priority date
Expiry dateApr 29, 2039

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The instant disclosure provides antibodies that specifically bind to T-cell immunoreceptor with Ig and ITIM domains (TIGIT) (e.g., human TIGIT) and antagonize TIGIT function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.