Derivation of human skin organoids from pluripotent stem cells
US11021688B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Oct 21, 2016 |
| Grant date | Jun 1, 2021 |
| Priority date | — |
| Expiry date | Feb 8, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/136
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods for directing differentiation of human pluripotent stem cells into a three-dimensional multilayered skin composition comprising an epidermal layer, a dermal layer, and a plurality of cells capable of forming a functional hair follicle. Also provided herein are three-dimensional, multilayered engineered skin compositions and methods of using the same for drug screening, for screening compounds for effects on hair growth, and for other applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.