Methods for forming lipid bilayers on biochips
US11021745B2 · kind B2 · utility
1Cited by
115References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 11, 2019 |
| Grant date | Jun 1, 2021 |
| Priority date | — |
| Expiry date | Feb 11, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48721
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This disclosure provides a biochip comprising a plurality of wells. The biochip includes a membrane that is disposed in or adjacent to an individual well of the plurality of wells. The membrane comprises a nanopore, and the individual well comprises an electrode that detects a signal upon ionic flow through the pore in response to a species passing through or adjacent to the nanopore. The electrode can be a non-sacrificial electrode. A lipid bilayer can be formed over the plurality of wells using a bubble.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.