Compositions and methods for preventing and reducing inflammation and treating disorders associated with inflammation
US11026992B2 · kind B2 · utility
0Cited by
3References
13Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 21, 2019 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Jun 21, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions and methods for preventing and reducing inflammation and preventing and treating diseases and disorders associated with inflammation. It has been shown that CRADD plays a pivotal role in maintaining the integrity of endothelial monolayers. The recombinant cell-penetrating CRADD protein (CP-CRADD)-based compositions and methods described herein provide for the development of a novel treatment for inflammatory vascular disorders including cardiovascular, cerebrovascular, respiratory, gastrointestinal, and renal systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.