Reduction of in vitro genotoxicity of pollen extracts by removal of flavonoids
US11027010B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Jan 26, 2017 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Aug 25, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to grass pollen extracts containing reduced amount of flavonoid glycosides in order to minimize the risks of genotoxicity of the grass pollen extracts. The invention also relates to a method of preparing grass pollen extracts containing reduced amount of flavonoid glycosides by ultrafiltration. Flavonoid glycosides are naturally present in grass pollen extracts and they have been identified as being responsible for the formation of flavonoid aglycones, which are genotoxic in vitro, under the influence of enzymes contained in the grass pollen extracts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.