PCI method for generating immune respose to antigenic molecule using checkpoint inhibitor and TLR3 ligand
US11027017B2 · kind B2 · utility
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2References
11Claims
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Inventor
Key dates
| Filing date | Mar 4, 2016 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Apr 24, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns a method of generating an immune response in a subject, comprising administering to the subject an antigenic molecule, a photosensitizing agent, a checkpoint inhibitor, and irradiating said subject with light of a wavelength effective to activate the photosensitizing agent to generate an immune response. Preferably the method is a method of vaccination. The invention also provides related methods, compositions, cells, uses, products and kits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.