Conjugates and conjugating reagents
US11027022B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 19, 2017 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Aug 6, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A conjugate of a protein or peptide conjugated to a therapeutic, diagnostic or labelling agent via a linker, in which the linker includes a protein or peptide bonding portion having the general formula: in which Pr represents said protein or peptide, each Nu represents a nucleophile present in or attached to the protein or peptide, each of A and B independently represents a C1-4alkylene or alkenylene chain, and W′ represents an electron withdrawing group or a group obtained by reduction of an electron withdrawing group; and in which the linker also includes a cyclodextrin. The invention also provides reagents for making such conjugates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.