Compound for treating metabolic diseases and preparation method and use thereof
US11028111B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Aug 15, 2018 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Aug 15, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J51/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are a compound for treating metabolic diseases having the structure as shown in formula (I) or formula (II), or a racemate, stereoisomer, geometric isomer, tautomer, solvate, hydrate, metabolite, pharmaceutically acceptable salt or prodrug thereof. The compound is an activator of FXR and/or a TGR5 receptor, and thus has the activity of activating FXR and/or a TGR5 receptor, and can be used in the preparation of drugs for treating chronic liver diseases, metabolic diseases or portal hypertension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.