Phytase variants YkAPPA having improved pepsin resistance and increased catalytic efficiency
US11028377B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jan 15, 2018 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Jan 15, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to the field of genetic engineering, particularly to phytase variants YkAPPA having amino acid sequence substituting Leucine at the 162th site of the sequence set forth in SEQ ID NO.1 with glycine or proline, or having amino acid sequence substituting glutamic acid at the 230th site of the sequence set forth in SEQ ID NO.1 with glycine, alanine, serine, threonine, aspartic acid, proline, or arginine, and having improved pepsin resistance and increased catalytic efficiency of 2.1 times of that of the wild phytase, in the benefit of the development of economical feed enzyme industry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.