Optimal index sequences for multiplex massively parallel sequencing
US11028435B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 1, 2018 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Jan 7, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B30/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The disclosed embodiments concern index oligonucleotides configured to identify sources of samples of nucleic acids and methods, apparatus, systems and computer program products for identifying and making the index oligonucleotides. In some implementations, the index oligonucleotides include a set of index sequences, a Hamming distance between any two index sequences of the set of index sequences meeting one or more criteria. System, apparatus, and computer program products are also provided for determining a sequence of interest using the index oligonucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.