Transgenic chicken for production of antibodies having a common light chain
US11033009B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 24, 2016 |
| Grant date | Jun 15, 2021 |
| Priority date | — |
| Expiry date | Feb 14, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This disclosure provides, among other things, a transgenic animal and a method of using the same to make antibodies that have a common light chain. In certain embodiments, the transgenic animal may comprising a genome comprising a common light chain transgene, wherein the common light chain transgene comprises a non-immunoglobulin light-chain promoter and a common light-chain coding sequence. In certain embodiments, the common light chain is constitutively expressed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.