Carbohydrate derivatives used for surface modification of immune cells, use thereof and method thereof
US11033562B2 · kind B2 · utility
0Cited by
0References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 14, 2020 |
| Grant date | Jun 15, 2021 |
| Priority date | — |
| Expiry date | Feb 14, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure discloses carbohydrate derivatives used for surface modification of immune cells, use thereof, and method thereof. The carbohydrate derivatives are 9-carbon monosaccharide sialic acid derivatives modified at C9 position by targeting substituents. The surfaces of the immune cells (T cells, NK cells, macrophages, DC cells, B cells, or granulocytes) is modified by the carbohydrate derivatives to obtain modified immune cells, so that the modified immune cells can be used for treatment of tumors or other diseases to obtain good effects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.