Patent · US Active

Polysaccharide and methods

US11033632B2 · kind B2 · utility

0Cited by
1References
12Claims
0Family size

Inventors

Key dates

Filing dateNov 3, 2017
Grant dateJun 15, 2021
Priority date
Expiry dateNov 3, 2037

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2400/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

There is provided a molecule comprising a chain of seven or more contiguous units of 4,6-dideoxy-4-acylamido-α-pyranose, each pair of units joined by a C1-C2 or a C1-C3 link, the chain having a terminal end and a reducing end, wherein the pyranose ring in the unit of the chain most distal from the reducing end is linked to a cap structure. The cap structure is not a 4,6-dideoxy-4-acylamido-α-pyranose. There are also provided vaccine compositions comprising the molecule and methods of vaccinating an animal NI against infection by a Brucella organism, including methods of distinguishing between a vaccinated and an infected animal. There are further provided novel methods of detecting the presence in a sample of an anti-Brucella antibody.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.