Methods for electroelution of biomolecules

US11033859B2 · kind B2 · utility

Assignee

• Global Life Sciences Solutions Operations UK Limited · GB

Inventors

• Christopher Michael Puleo · Niskayuna, US
• John Richard Nelson · Fryeburg, US
• Patrick McCoy Spooner · Slingerlands, US
• Ralf Lenigk · Niskayuna, US
• Nicole Lea Wood · Niskayuna, US
• Li Zhu · San Jose, US
• Craig Patrick Galligan · Niskayuna, US

Key dates

• Filing date: Jun 19, 2018
• Grant date: Jun 15, 2021
• Expiry date: Aug 2, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/101
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

A method of eluting biomolecules, such as nucleic acids from a biological sample by electroelution is provided. An example of a method includes various steps, such as loading the biological sample to a device comprising a housing, at least two conductive redox polymer electrodes operationally coupled to the housing and a biomolecule impermeable layer disposed on at least one of the electrodes. The loading of sample is followed by initiating an electrical connection to generate an electric field strength sufficient to elute biomolecules from the biological sample; and eluting the biomolecules from the biological sample.