Compositions and methods for treating leber's hereditary optic neuropathy
US11034954B2 · kind B2 · utility
3Cited by
13References
23Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 31, 2020 |
| Grant date | Jun 15, 2021 |
| Priority date | — |
| Expiry date | Mar 31, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein is a recombinant nucleic acid, comprising: a mitochondrial targeting sequence; a mitochondrial protein coding sequence, wherein said mitochondrial protein coding sequence encodes a polypeptide comprising a mitochondrial protein; and a 3′UTR nucleic acid sequence. Also disclosed is a pharmaceutical composition comprising the recombinant nucleic acid and a method of treating Leber's hereditary optic neuropathy (LHON) using the pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.