Lipids and lipid nanoparticle formulations for delivery of nucleic acids
US11040112B2 · kind B2 · utility
20Cited by
67References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 8, 2018 |
| Grant date | Jun 22, 2021 |
| Priority date | — |
| Expiry date | Nov 8, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y113/12007
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds are provided having the following structure: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, L1, L2, G1, G2 and G3 are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.