Cell culture
US11041145B2 · kind B2 · utility
0Cited by
6References
3Claims
0Family size
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Key dates
| Filing date | Aug 17, 2017 |
| Grant date | Jun 22, 2021 |
| Priority date | — |
| Expiry date | Aug 17, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/27
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
There is described an isolated 3-dimensional liver spheroid wherein said spheroid has: increased ATP content as compared to a 3-dimensional liver spheroid cultured in Complete William's E medium alone; the same or increased activity of cytochrome P450 1A1 and cytochrome P450 1B1 as compared to a 3-dimensional liver spheroid cultured in Complete William's E medium alone; and increased albumin secretion as compared to a 3-dimensional liver spheroid cultured in William's E medium alone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.