Patent · US Active

Modified lysine decarboxylase enzymes

US11041177B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignees

Cathay Biotech Inc. · CN
CIBT America Inc. · US

Inventors

Howard Chou · Shanghai, CN
Wenqiang Lu · Shanghai, CN
Ling Chen · Shanghai, CN
Xiucai Liu · Shanghai, CN

Key dates

Filing date	Dec 30, 2016
Grant date	Jun 22, 2021
Priority date	—
Expiry date	Dec 30, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y401/01018
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mutant polypeptides, and methods of generating such microorganism.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.