Mycobacteriophages capable of delivering auto-luminescent elements and uses thereof
US11041184B2 · kind B2 · utility
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Key dates
| Filing date | Sep 7, 2018 |
| Grant date | Jun 22, 2021 |
| Priority date | — |
| Expiry date | Jan 24, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/35
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A mycobacteriophage capable of delivering an auto-luminescent element includes luxCDABE genes for auto-luminescence of a host bacterium. The auto-luminescent element is located on a transposon, and can be randomly inserted into the host genome with the transposon. The mycobacteriophage can be used for rapid detection of a live host bacterium in a sample and detection of sensitivity of the host bacterium to a drug or drug combination.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.