Methods for assessing a genomic region of a subject
US11041203B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 13, 2014 |
| Grant date | Jun 22, 2021 |
| Priority date | — |
| Expiry date | May 23, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention generally relates to method for assessing a genomic region of a subject. In certain embodiments, methods of the invention involve obtaining a sample including nucleic acid from a subject. The nucleic acid includes a target sequence from a target genomic region and a paralogous sequence from a non-target genomic region. The target sequence and the paralogous sequence are isolated from the sample. The target sequence and the paralogous sequence are sequenced to obtain sequence reads that include target sequence reads and paralogous sequence reads. The paralogous sequence reads are excluded, and the genomic region of the subject are assessed based on the target sequence reads.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.