Irreversible electroporation through a combination of substance injection and electrical field application
US11045648B2 · kind B2 · utility
3Cited by
40References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 13, 2018 |
| Grant date | Jun 29, 2021 |
| Priority date | — |
| Expiry date | Oct 3, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2018/1472
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Biological cell destruction is achieved through a combination of injection of a substance and application of an electrical field. The substance, such as a cationic polymer, is selected for its electrical characteristics which can add to the transmembrane electric field of a cell when the electrical field is applied. In some examples, electrical field application is performed to encourage spatial concentration of the injected substance favorable to increased transmembrane field strength. The biological cell or cells are destroyed primarily through irreversible electroporation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.