Entecavir intermediate, synthetic method thereof and synthetic method for entecavir
US11046663B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Sep 25, 2018 |
| Grant date | Jun 29, 2021 |
| Priority date | — |
| Expiry date | Sep 25, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The disclosure relates to an entecavir intermediate, a synthetic method therefor, and the synthetic method for entecavir by using the intermediate. According to the disclosure, the synthetic methods for entecavir and the intermediate thereof have the advantages of being controllable in chirality, high in yield and product purity, wide in source of raw materials, cheap and available in reagents, simple in reactions, convenient to operate, environmentally friendly, and suitable for industrial amplification production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.