Salt of cetagliptin, preparation method thereof, pharmaceutical composition, and use thereof
US11046701B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | May 29, 2018 |
| Grant date | Jun 29, 2021 |
| Priority date | — |
| Expiry date | May 29, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a salt of a compound of formula (I), The salt is crystalline or amorphous phosphate, or crystalline or amorphous oxalate. Particularly, a crystal form B of the phosphate of the present invention has high crystallinity, low hygroscopicity and good stability, and the crystal form B of the phosphate is good in oral bioavailability, good in tolerance after long-term administration, difficult to induce hypoglycemia and good in inhibition effect on serum DPPIV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.