Recombinant yeast strains for pentose fermentation

US11046938B2 · kind B2 · utility

Assignee

• Novozymes A/S · DK

Inventors

• Kaisa Karhumaa · Södra Sandby, SE
• Malin Sendelius · Lund, SE
• Violeta SÁNCHEZ I NÓGUE · Lund, SE

Key dates

• Filing date: Dec 19, 2017
• Grant date: Jun 29, 2021
• Expiry date: Dec 19, 2037

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02E50/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Described herein are recombinant yeast cells expressing a xylulose kinase (XK) which are suitable for fermentation of pentoses. Also described are recombinant yeast cells with higher tolerance to formic and/or acetic acid and suitable for fermentation of pentoses. Also described are recombinant yeast cells expressing an enolase, a phosphofructokinase beta subunit, a 6-phosphofructo-2-kinase, a glucose-6-phosphate isomerase, a phosphoglycerate mutase and/or a triose-phosphate isomerase, and suitable for fermentation of pentoses. Also described are recombinant yeast cells expressing a phosphoglucomutase and/or phosphoribomutase which are suitable for fermentation of pentoses. Further described are methods of using or producing such recombinant yeast cells and related materials.