Mechanical transfection devices and methods
US11046976B2 · kind B2 · utility
3Cited by
14References
19Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 24, 2018 |
| Grant date | Jun 29, 2021 |
| Priority date | — |
| Expiry date | Jun 21, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/87
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Systems and methods for transfection devices are contemplated for delivery of various complex macrostructures. Preferred systems and methods are suitable for mRNA reprogramming and genome editing and use mechanical force to induce uptake of the macrostructures in a target cell. Contemplated devices are able to achieve high throughput of transfected cells in remarkably short time that remain viable and are capable of producing colonies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.