Patent · US Active

IGFBP7 for diagnosing diastolic dysfunction

US11047866B2 · kind B2 · utility

0Cited by

7References

10Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Johann Karl · Peißenberg, DE
Ursula-Henrike Wienhues-Thelen · Krailling, DE
Dirk Block · Bichl, DE
Christian Zaugg · Rheinfelden, CH
Hans-Peter Brunner · Münchenstein, CH
James Januzzi · Wellesley, US
Andre Ziegler · Läufelfingen, CH
Julian Braz · Greenwood, US
Thomas Dieterle · Freiburg (Elbe), DE
Edelgard Kaiser · Chur, CH

Key dates

Filing date	May 23, 2019
Grant date	Jun 29, 2021
Priority date	—
Expiry date	May 23, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/325
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Presented is a method for diagnosing and/or grading diastolic dysfunction or at least one structural or functional abnormality associated with diastolic dysfunction. The method involves measuring the level of IGFBP7 (Insulin like growth factor binding protein 7) and, optionally, the level of at least one further marker in a patient suffering from heart failure, and comparing the level to a reference level. Further envisaged is a method of monitoring diastolic function in a patient suffering from heart failure. Also described are kits and devices adapted to carry out the method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.