Patent · US Active

Method for longitudinal relaxation time measurement in inhomogeneous fields

US11047943B2 · kind B2 · utility

0Cited by

0References

9Claims

0Family size

Assignee

XIAMEN UNIVERSITY · CN

Inventors

Shuhui Cai · Shantou, CN
Hao Chen · Plano, US
Zhong Chen · Cedar Park, US

Key dates

Filing date	Dec 27, 2017
Grant date	Jun 29, 2021
Priority date	—
Expiry date	Dec 9, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG01R33/5615
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A protocol to determine chemical shift-specific Ti constants in inhomogeneous magnetic fields is provided. Based on intermolecular double-quantum coherences and spatial encoding techniques, the method can resolve overlapped NMR spectral peaks in inhomogeneous magnetic fields acquired using conventional methods. With inversion recovery involved, the amplitude of spectral peak will be modulated by inversion recovery time. After fitting the spectral peak amplitude variation curve, the corresponding longitudinal relaxation time can be achieved. With the measured T1 values in inhomogeneous magnetic fields, insights into chemical exchange rates, signal optimization, and data quantitation can be obtained.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.