Urokinase-type plasminogen activator transgenic mouse
US11051496B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Mar 23, 2018 |
| Grant date | Jul 6, 2021 |
| Priority date | — |
| Expiry date | Oct 11, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/146666
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a mouse with liver damage, having a high degree of damage against the mouse's original hepatocytes while having a uPA gene in a heterozygous form, and a method for efficiently preparing the mouse. Specifically, the method for preparing a mouse with liver damage having the uPA gene in a heterozygous form comprises the following steps of:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.