Ras protein degradation inducing molecule and pharmaceutical composition
US11052154B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Nov 13, 2017 |
| Grant date | Jul 6, 2021 |
| Priority date | — |
| Expiry date | May 26, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A Ras protein degradation inducing molecule that can induce degradation of Ras proteins, and a pharmaceutical composition that contains this Ras protein degradation inducing molecule are provided. The Ras protein degradation inducing molecule is a conjugate of a Ras protein affinity molecule which has affinity to Ras proteins, and a proteolysis-inducing tag which has affinity to protease and does not inhibit proteolysis of proteins by the protease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.