Plant-produced chimaeric Orbivirus VLPs
US11053509B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 19, 2017 |
| Grant date | Jul 6, 2021 |
| Priority date | — |
| Expiry date | Apr 19, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2720/12134
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a second generation, plant-produced synthetic Orbivirus candidate vaccine. The vaccine comprises a plant produced chimaeric Orbivirus virus like particle (VLP) comprising at least one structural protein from one Orbivirus serotype and at least one structural protein selected from another serotype of the Orbivirus, wherein both structural capsid proteins are from the same Orbivirus species. In particular the invention relates to a vaccine against an Orbivirus, a method of producing chimaeric Orbivirus virus-like particles (VLPs) for use in a method of prevention and/or treatment of an Orbivirus infection, the use of the chimaeric Orbivirus VLPs in the manufacture of a vaccine for an Orbivirus, and a method of preventing and/or treating an Orbivirus infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.