Mitochondrial markers of neurodegenerative diseases
US11053549B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Mar 27, 2015 |
| Grant date | Jul 6, 2021 |
| Priority date | — |
| Expiry date | Nov 25, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is an in vitro method to diagnose or determine the risk of developing a neurodegenerative disease in a subject based on the determination of the methylation pattern in certain regions of mitochondrial DNA from the subject or the determination of the nucleotide at the polymorphic position 16519 in the mitochondrial DNA of the subject. Also, disclosed are nucleic acids suitable for the in vitro method to diagnose or determine the risk of developing a neurodegenerative disease in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.