Estimating the probability of matrix factorization results
US11055380B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 9, 2018 |
| Grant date | Jul 6, 2021 |
| Priority date | — |
| Expiry date | Apr 3, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16C20/70
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A method for ranking a relationship between drugs and adverse events includes creating a matrix of associations between a plurality of drugs and a plurality of adverse events and factoring the matrix of associates into a pair of matrix factors. The matrix factors, when multiplied, approximate the matrix of associations, and a product of the matrix factors is a matrix of observed scores. The method further includes determining, for each drug and adverse event pair in the matrix of observed scores, a z-score, an expected score for each drug and adverse event pair, and a standard deviation for each drug and adverse event pair, calculating a probability of a relationship between a drug and adverse event using the z-score for the drug and adverse event pair, and determining that the drug and adverse event are related, when the probability of a relationship is greater than a predetermined magnitude.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.