Tissue structure and preparation method thereof
US11060065B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 9, 2014 |
| Grant date | Jul 13, 2021 |
| Priority date | — |
| Expiry date | Sep 24, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/28
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A tissue structure for enabling comprehensive understanding of gene patterns of mature cells and a method of preparing the tissue structure are provided. A tissue structure is obtained by co-culturing an endodermal, ectodermal, or mesodermal cell derived from a stem cell and at least one cell and/or factor selected from the group consisting of a vascular cell, a mesenchymal cell, a factor secreted by a vascular cell, a factor secreted by a mesenchymal cell, and a factor secreted when both a vascular cell and a mesenchymal cell exist. A value obtained by assay of a plurality of functions using a Pearson product-moment correlation coefficient is closer to a value of a cell or biological tissue sampled from an adult than a value of a cell or biological tissue sampled from a fetus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.