Method and system for obtaining and using pharmacokinetic data in drug administration
US11062797B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Oct 12, 2015 |
| Grant date | Jul 13, 2021 |
| Priority date | — |
| Expiry date | Dec 29, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/502
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
There is provided a method for dosing a drug to a patient, including (a) administering the drug to the patient according to a titration dosing schedule, where the titration dosing schedule is determined from a database storing data containing observations of previous patient responses to the drug, and the titration dosing schedule is associated with a subcohort of a cohort of patients, where a subcohort classification is based on one or more factors associated with variability of the drug; (b) monitoring the patient during the administering (a) to determine when a desired clinical endpoint is reached; (c) administering the drug to the patient according to a maintenance dosing schedule, where the maintenance dosing schedule is based on an estimate of drug level, where the estimate is based on (i) when the desired clinical endpoint is reached, and (ii) a pharmacokinetic model for the subcohort; and (d) updating the database to incorporate data from the monitoring (b) of the patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.