Mutant Bordetella strains and methods of use
US11065276B2 · kind B2 · utility
3Cited by
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1Claims
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Inventors
Key dates
| Filing date | Apr 30, 2020 |
| Grant date | Jul 20, 2021 |
| Priority date | — |
| Expiry date | Apr 30, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of reducing or preventing the development of airway inflammation in a subject includes the step of infecting the respiratory tract of a subject an amount of a composition including a pharmaceutically acceptable carrier and live attenuated pertactin-deficient Bordetella bacteria sufficient to colonize the respiratory tract of the subject. The step of infecting the subject with the live attenuated pertactin-deficient Bordetella bacteria results in reduction or prevention of the development of airway inflammation in the subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.