Patent · US Active

Complex coacervate for controlled release and related methods

US11065337B2 · kind B2 · utility

0Cited by

2References

13Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

Eric M. Jeffries · West New York, US
Yadong Wang · Wexford, US

Key dates

Filing date	Dec 14, 2016
Grant date	Jul 20, 2021
Priority date	—
Expiry date	Dec 14, 2036

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are coacervate compositions including cytokines, and methods of making and using the same. The coacervate can be formed by the mixing of an active agent, such as a drug or protein with the polyanion, such as heparin or heparan sulfate, and a custom-made polycation (e.g., PEAD or PELD). The coacervates can be used in the treatment of diseases and disorders where targeted treatment is desired, for example in treatment of cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.