Compound bearing beta-galactoside-introduced self-immolative linker
US11065343B2 · kind B2 · utility
2Cited by
15References
14Claims
0Family size
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Key dates
| Filing date | Dec 28, 2017 |
| Grant date | Jul 20, 2021 |
| Priority date | — |
| Expiry date | Apr 16, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a compound bearing a self-immolative linker having β-galactoside-introduced thereto. In a compound bearing a β-galactoside-introduced self-immolative linker according to the present invention, particularly, the self-immolative linker may form a glycosidic bond with a protein (e.g., an oligopeptide, polypeptide, an antibody, etc.) or ligand which has specific affinity for a desired target or with an active agent (e.g., a drug, a toxin, a ligand, a detection probe, etc.), which has a specific function or activity so as to allow the selective release of the active agent within a target cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.