Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents
US11066355B2 · kind B2 · utility
14Cited by
66References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 18, 2020 |
| Grant date | Jul 20, 2021 |
| Priority date | — |
| Expiry date | Sep 18, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C229/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure features novel lipids and compositions involving the same. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.