Biodegradable surfactants and related compositions, methods and systems

US11066359B2 · kind B2 · utility

Assignee

• Lawrence Livermore National Security, LLC · US

Inventors

• Mathew Gerald Lyman · Brentwood, US
• Lawrence C. Dugan · Modesto, US
• Roald N. Leif · San Ramon, US
• Bonnee Rubinfeld · Danville, US
• Brian E. Souza · Livermore, US
• Carlos Valdez · San Ramon, US

Key dates

• Filing date: Feb 8, 2018
• Grant date: Jul 20, 2021
• Expiry date: Feb 8, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/596
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Biodegradable surfactants are described, in which an amphiphilic heteroatom containing hydrocarbon optionally comprising at least one counterion (Z), and related compositions, methods and systems. Biodegradable surfactant described herein has an aHLB value in accordance with equation (1): aHLB=20*Gh/(Gh−Gt) (1) wherein Gh is the Group Number of a hydrophilic head portion of the biodegradable surfactant optionally comprising the at least one counterion (Z), and Gt is the Group Number of a hydrophobic tail portion of the biodegradable surfactant. A biodegradable surfactant in the sense of the disclosure can be tuned to a set hydrophilic-lipophilic balance (aHLB) by selectively modifying at least one tuning moiety of the biodegradable surfactants to provide tuned biodegradable surfactants having an increase or decrease in their adjusted hydrophilic-lipophilic balance (aHLB).