Patent · US Active

Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof

US11066373B2 · kind B2 · utility

0Cited by

23References

17Claims

0Family size

Assignee

CHIMERIX, INC. · US

Inventors

Roy W. Ware · Raleigh, US
Aaron Leigh Downey · Durham, US

Key dates

Filing date	Oct 11, 2019
Grant date	Jul 20, 2021
Priority date	—
Expiry date	Oct 11, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/53
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.