Compositions comprising TREM2 and methods of use thereof
US11066456B2 · kind B2 · utility
0Cited by
11References
7Claims
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Key dates
| Filing date | Feb 24, 2017 |
| Grant date | Jul 20, 2021 |
| Priority date | — |
| Expiry date | Feb 24, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides TREM2 constructs. TREM2 constructs of the invention are polynucleotide sequences encoding a polypeptide, wherein the polypeptide comprises at least one TREM2 or fragment thereof and a targeting moiety and optionally comprising a signal peptide and/or a purification moiety. The present invention also provides isolated polypeptides encoded by TREM2 constructs, vectors comprising TREM2 constructs, isolated cells comprising said vectors, and methods of use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.